
何健:您通过核磁共振测定蛋白质三维结构的方法 Your way, the NMR method of determining the 3D structure of proteins 让您摘得了诺贝尔奖的桂冠 Gave you the honor of the Nobel Prize 这些年来通过您的核磁共振测定法 Over the years, with your way of using NMR 许多蛋白质结构都已经被成功测定 You have successfully determined the structures of many proteins 但是随着科技不断发展 But as the technology develops 新的分析方法正在出现 There are new ways emerging for the analysis 可以测定蛋白质三维结构 And determining of the 3D structure of proteins 比如现在已知的冷冻电子显微镜 We know currently we have the cryo-electron microscopy 它在分辨率方面已经超过了核磁共振 It has surpassed NMR in terms of resolution 但您仍在强调核磁共振的重要性和意义 But you still emphasize the importance and the significance of NMR 核磁共振技术为何如此特别呢? What makes NMR technology so unique and so special? Kurt:我们越是能够仔细观察活性有机体 The closer we get to the functioning organism 研究生物体结构中分子的相互作用 And study molecular interactions within the framework of the living organism 我们就越能揭开生命运作的奥秘 #知识前沿派对 #核磁共振 #诺贝尔奖 #冷冻电镜 #蛋白质动态结构